Computational biomimetics and bioengineering 3D printing to develop a personalized regenerative biological ventricular assist device to provide lasting functional support to damage hearts.

BRAV3

Detalles del proyecto

Abbreviation: BRAV3

Start date: 2020-01-01End date: 2024-12-31

Budget: 8.000.000 €

Centre bugdet: 579.000 €

Funding: Programa H2020: 579.000 €

Description

The main aim of this project is to make a qualitative leap in the treatment of infarcted heart diseases. The majority of treatments of chronic infarcted hearts are pharmaceutical and include the use of ventricular assist devices (VADs) that consist of a mechanical pump that supports heart function and blood flow.

This project will seek to generate customised biological tissue using 3D printing technologies (bioprinting and electrospinning), making it possible to generate a construct with optimal replication of the mechanical properties of the native myocardium and which is capable of delivering signals for alignment with the cardiac cells that will populate it.  These cells will not only provide the ability to contract, they will also form a functional vascular network.

Participants
  • University of Navarra
  • University of Eindhoven
  • University of Leuven
  • Boston Scientific
  • Ibet
  • University of Würzburg
  • Ibec
  • Ebers
  • University of Zaragoza
  • PNO
  • University of Utrecht
  • SERMAS
  • AE Medicalis
Activities carried out by Leartiker

Leartiker has performed the following activities:

  • Design and development of a bioreactor that also enables the electromechanical and metabolic maturation of the customised tissue.  The biological ventricular assist device (BioVAD) will deliver lasting functional support to damaged hearts.
  • Design and development of the BioVad patient insertion system, together with the medical team.
USE OF COOKIES

This website uses its own and third-party cookies in order to offer you the best possible user experience.

Before continuing, you must decide what to do with these cookies. You can accept all or save the selection you make.

OWN COOKIES

We use the technical cookies necessary for the operation of the website and we save your preferences for cookie settings and chosen language.

THIRD PARTY COOKIEES

We use third-party sites to analyze browsing and to display embedded information (YouTube and Flickr). Activate the desired options.

Not accepting third-party cookies will mean that we do not show you certain content. Although we will show you a link to access them.

For more information see: Privacy policy